Thick and full tone close to a cross between Hendrix and Muddy Waters.
Use lo-gain input on the amp for the guitar. Run the effects unit through the loop on the rear of the amp. Set gain control on peddle to 3/4. Then use clean channel on the amp. Set bass on the amp at 3/4, mid on amp at 1/2, and treble on amp between 1/2 and 3/4.